Renal Cell Carcinoma
Renal cell carcinoma (RCC) represents 2-3% of all cancers. Learn more about this disease, its diagnosis and treatments.
Many renal masses remain asymptomatic until the late stages of the disease.
Currently, more than 50% of RCCs are detected incidentally when non-invasive imaging is used to investigate a variety of nonspecific symptoms and other abdominal diseases . The classic triad of flank pain, gross haematuria, and palpable abdominal mass is now rare (6-10%) and correlates with advanced disease.
Paraneoplastic syndromes are found in approximately 30% of patients with symptomatic RCCs. Most common paraneoplastic syndromes are: Hypertension, cachexia, weight loss, pyrexia, neuromyopathy, amyloidosis, elevated erythrocyte sedimentation rate, anemia, abnormal liver function, hypercalcemia and polycythemia
Physical examination has only a limited role in the diagnosis of RCC. However, the following findings should prompt radiological examinations: Palpable abdominal mass; palpable cervical lymphadenopathy; non-reducing varicocele and bilateral lower extremity oedema, which suggests venous involvement .
If symptoms or the results of the physical exam suggest kidney cancer, more tests will probably be performed including lab tests and imaging tests
- Lab tests
- Complete blood count (CBC)
- Blood chemistry tests
- Imaging tests
- Computed tomography (CT) scans, magnetic resonance imaging (MRI) scans, and ultrasound can be very helpful in diagnosing most kinds of kidney tumors, although patients rarely need all of these tests.
- Other tests, such as chest x-rays and bone scans, are more often used to help determine if the cancer has spread (metastasized) to other parts of the body.
of all cancers
renal masses remain asymptomatic
is the first treatment option
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